The risk assessments are currently a prototype and not for clinical use.

About CancerPDX

The University Hospitals of Leicester (UHL) clinical genetics department have collaborated with CancerPDX to develop a new free and confidential online family history taking tool for patients that have been referred to the clinical genetics department.

PDXTriage helps patients and healthcare professionals to work out if there is likely to be an inherited link or single gene that has helped cause cancer in the family. It can also assess whether a family history of breast, ovarian or prostate cancer is likely to benefit from a referral for genetic counselling or testing.

PDXFamily can then help identify who in the family might be at risk and when they might benefit from genetic screening or genetic counselling. PDXFamily can also flag to clinicians particular patterns that might suggest a single high risk susceptibility gene alteration such as the BRCA1 gene that has affected the family of the actress, Angelina Jolie.

Why have we developed this?

To improve communication between patients, their general practitioner and specialist services to simplify and speed up processes, aid decision-making and improve sign-posting to the most effective service to help patients.

Do I have to use it?

This is OPTIONAL and if you have concerns over confidentiality or are uncomfortable using computers, you are most welcome to use the paper copy of the family history questionnaire we have developed and used over many years.


Through submitting your family history information using PDXFamily you will automatically be informed when this has been received by the clinical genetics department and notified via email when an appointment has been recommended. If you choose not to use PDX, and would prefer to use the paper family history form instead, your referral will be processed in the usual manner. A further advantage with PDXFamily is that you will be able to easily print out, store and amend your online family history record in a diagram format, anytime.

How do I use the system?

Please see this short video on how to submit your family history information on CancerPDX.
Don’t forget to add all your blood relatives, including those who have and have not been diagnosed with cancer, as this helps us assess your family history more accurately.
Do not worry if you have limited details on names, type of cancer or age of onset. The clinical genetics team can always check this with your support at a later stage if this is important.
Do not worry if you are struggling to use the system, you can call the genetics team on 0116 258 5736 or submit what you can.